Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomewide association analysis on green tea chemoprevention of colorectal adenoma: the importance of SLCO1A2 variants.

Pharmacogenomics - 1 Jan 2025

Stingl J, Scholl C, Steffens M, Koczera P, Muche R, Rohlmann F, Ettrich Th, Seufferlein Th

Abstract excerpt

BACKGROUND: Green tea extract was tested for the secondary prevention of colorectal adenoma in the placebo-controlled MIRACLE trial. Genome-wide screening on adenoma recurrence was performed in n = 550 participants 3 years after randomization to green tea or placebo intake. METHODS: Single Marker Analysis followed by regression analyses was calculated for all 700.078 markers assuming an additive genetic model and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Aged
Share to Chemoprevention

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Genome-Wide Association Study

Share to Organic Anion Transporters

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 40433816
DOI: 10.1080/14622416.2025.2510186
PMCID: PMC12203844

Genes

SLCO1A2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomewide association analysis on green tea chemoprevention of colorectal adenoma: the importance of SLCO1A2 variants.PMID 40433816Read ↗

DNA repair gene polymorphisms and tobacco smoking in the risk for colorectal adenomas.Semantic proximity Read ↗

Common variants in glucuronidation enzymes and membrane transporters as potential risk factors for colorectal cancer: a case control study.Semantic proximity Read ↗

Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma.Semantic proximity Read ↗

SLCO1B3 and SLCO2B1 genotypes, androgen deprivation therapy, and prostate cancer outcomes: a prospective cohort study and meta-analysis.Semantic proximity Read ↗

Vitamin D Receptor Genotype, Vitamin D3 Supplementation, and Risk of Colorectal Adenomas: A Randomized Clinical Trial.Semantic proximity Read ↗

PLA2G4A mutants modified protective effect of tea consumption against colorectal cancer.Semantic proximity Read ↗

No evidence that associations of incident, sporadic colorectal adenoma with its major modifiable risk factors differ by chromosome 8q24 region rs6983267 genotype.Semantic proximity Read ↗

Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trial.Semantic proximity Read ↗

Impact of genetic polymorphisms on adenoma recurrence and toxicity in a COX2 inhibitor (celecoxib) trial: results from a pilot study.Semantic proximity Read ↗

Cats with Genetic Variants of AGXT2 Respond Differently to a Dietary Intervention Known to Reduce the Risk of Calcium Oxalate Stone Formation.Semantic proximity Read ↗

Genetic variation in SLC7A2 interacts with calcium and magnesium intakes in modulating the risk of colorectal polyps.Semantic proximity Read ↗

Risk modification of colorectal adenoma by CYP7A1 polymorphisms and the role of bile acid metabolism in carcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.