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Article

Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma.

Nutrition and cancer - 1 Jan 2008

Erichsen Hans Christian, Peters Ulrike, Eck Peter, Welch Robert, Schoen Robert E, Yeager Meredith, Levine Mark, Hayes Richard B, Chanock Stephen

Abstract excerpt

Previous observational studies suggest that vitamin C may reduce risk of colorectal cancer. Vitamin C transport is facilitated by membrane bound sodium-dependent transporters, SVCT1 (encoded by SLC23A1) and SVCT2 (encoded by SLC23A2). To investigate if common genetic variants in these two genes are associated with risk of colorectal tumor development, we conducted a case-control study of 656 Caucasian advanced...

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Identifiers

PMID: 18791929
DOI: 10.1080/01635580802033110
PMCID: PMC3490215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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