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Article

Vitamin D Receptor Genotype, Vitamin D3 Supplementation, and Risk of Colorectal Adenomas: A Randomized Clinical Trial.

JAMA oncology - 1 May 2017

Barry Elizabeth L, Peacock Janet L, Rees Judy R, Bostick Roberd M, Robertson Douglas J, Bresalier Robert S, Baron John A

Abstract excerpt

IMPORTANCE: Despite epidemiological and preclinical evidence suggesting that vitamin D and calcium inhibit colorectal carcinogenesis, daily supplementation with these nutrients for 3 to 5 years was not found to significantly reduce the risk of recurrent colorectal adenomas in a recent randomized clinical trial. OBJECTIVE: To investigate whether common variants in 7 vitamin D and calcium pathway genes (VDR, GC,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27978548
DOI: 10.1001/jamaoncol.2016.5917
PMCID: PMC5580351

Genes

VDR
CASR
DHCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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