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Cats with Genetic Variants of AGXT2 Respond Differently to a Dietary Intervention Known to Reduce the Risk of Calcium Oxalate Stone Formation.

Genes - 28 Apr 2022

Hall Jean A, Panickar Kiran S, Brockman Jeffrey A, Jewell Dennis E

Abstract excerpt

This study was completed to evaluate a genotype-specific nutritional intervention for reducing the risk of calcium oxalate stone formation. Serum metabolomic profiles and genotypes of 445 cats in the colony at Hill’s Pet Nutrition, Inc (Topeka, KS, USA)were assessed in a genome-wide association study, and revealed an association between genetic variants of alanine-glyoxylate aminotransferase 2 (AGXT2) and...

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PMID: 35627178
DOI: 10.3390/genes13050791
PMCID: PMC9141165

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