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Article

Shared genetic architecture between leukocyte telomere length and Alzheimer's disease.

Alzheimer's research & therapy - 17 May 2025

Cao Zhi, Tan Qilong, Yang Hongxi, Xu Chenjie

Abstract excerpt

BACKGROUND: Epidemiological and clinical studies have reported an association between leukocyte telomere length (LTL) and Alzheimer's disease (AD). However, genetic association between the two phenotypes remains largely unknown. We aimed to elucidate the potential shared genetic architecture between LTL and AD. METHODS: Summary statistics from genome-wide association studies were obtained from large-scale biobank...

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Share to Alzheimer Disease
Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocytes

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 40382655
DOI: 10.1186/s13195-025-01757-z
PMCID: PMC12085009

Genes

APOE
DEXI
USP8

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