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Interactive Effects of Telomere Length and Genetic Variants on Alzheimer Disease Risk Across Multiple Ancestral Populations

2025-12-17

Abstract excerpt

<h4>Background</h4> Telomere length (TL), a biomarker of biological aging, but its association with Alzheimer’s disease (AD) remains unclear. <h4>Methods</h4> We estimated TL in whole-genome sequencing data from 35,014 Alzheimer’s Disease Sequencing Project participants using TelSeq, which after quality control yielded a dataset including 6,973 persons of European ancestry (EA), 4,188 African Americans (AA), 4,0...

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Literature Corpus work
4d395e2a-5bd7-5b1a-b086-8383a7a10363
DOI
10.64898/2025.12.15.25342309
Open publication

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Interactive Effects of Telomere Length and Genetic Variants on Alzheimer Disease Risk Across Multiple Ancestral PopulationsDOI 10.64898/2025.12.15.25342309
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