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Artificial intelligence–driven microsatellite instability profiling reveals distinctive genetic features in patients with lung cancer

29 Apr 2025

Abstract excerpt

BACKGROUND: Microsatellite instability (MSI) has emerged as a predictive biomarker for immunotherapy response in various cancers, but its role in non-small cell lung cancer (NSCLC) is not fully understood. METHODS: The authors used the bioinformatics tool MIAmS to assess microsatellite status from next-generation sequencing (NGS) data using a tailored microsatellite score. Immunohistochemistry (IHC) assays were...

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PMID: 40297960
DOI: 10.1002/cncr.35882

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