Article

DeltaMSI: Artificial Intelligence-based modeling of microsatellite instability scoring by next- generation sequencing

2022-05-31

Abstract excerpt

<h4>Background: </h4> DNA mismatch repair deficiency (dMMR) testing is crucial for detection of microsatellite unstable (MSI) tumors eligible for immunotherapy. MSI is detected by aberrant indel length distributions of microsatellite marker loci, either by operator-dependent visual inspection of PCR-fragment length profiles or by automated scoring using bioinformatic scripts on next-generation sequencing (NGS) dat...

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Literature Corpus work: dae153aa-2b0d-567b-a0e3-f3d3623de1a9
DOI: 10.21203/rs.3.rs-1645344/v1

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