Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acidic patch histone mutations and their effects on nucleosome remodeling.

Biochemical Society transactions - 29 Apr 2022

Dao Hai T, Pham Linh T D

Abstract excerpt

Structural and biochemical studies have identified a histone surface on each side of the nucleosome disk termed 'the nucleosome acidic patch' that acts as a regulatory hub for the function of numerous nuclear proteins, including ATP-dependent chromatin complexes (remodelers). Four major remodeler subfamilies, SWI/SNF, ISWI, CHD, and INO80, have distinct modes of interaction with one or both nucleosome acidic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Chromatin
Share to Chromatin Assembly and Disassembly

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histones

Share to Mutation

Share to Nucleosomes

Source

Identifiers

PMID: 35356970
DOI: 10.1042/BST20210773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acidic patch histone mutations and their effects on nucleosome remodeling.PMID 35356970Read ↗

Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding.Semantic proximity Read ↗

Mutations in non-acid patch residues disrupt H2A.Z's association with chromatin through multiple mechanisms.Semantic proximity Read ↗

Different modes of engagement with the nucleosome acidic patch yield distinct functional outcomesSemantic proximity Read ↗

Cancer Histone Mutations Impact Binding and DNA Repair Processes, Leading to Increased MutagenesisSemantic proximity Read ↗

Histone H2A.Z acid patch residues required for deposition and function.Semantic proximity Read ↗

Histone variants: nuclear function and disease.Semantic proximity Read ↗

Structure of the nucleosome-bound human BCL7ASemantic proximity Read ↗

Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosomeSemantic proximity Read ↗

Recognition and remodelling of nucleosomes and hexasomes by the human INO80 complexSemantic proximity Read ↗

The dynamics of histone H1 function in chromatin.Semantic proximity Read ↗

Regulation of ISWI involves inhibitory modules antagonized by nucleosomal epitopes.Semantic proximity Read ↗

CHD7 interacts with the nucleosome acidic patch for its efficient activity via its N-terminal regionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.