Article
Distinct lipoprotein contributions to valvular heart disease: Insights from genetic analysis.
International journal of cardiology - 15 Jul 2025
Luo Da, Björnson Elias, Wang Xiaoying, Zhang Bofang, Xu Changwu, Guan Yunlong, Xiang Shizhen, Borén Jan, Hao Xingjie, Chen Jing
Abstract excerpt
BACKGROUND: The per-particle pathogenicity of very-low-density lipoprotein (VLDL) and lipoprotein(a) [Lp(a)] with risk of valvular heart diseases (VHD) other than aortic stenosis compared with low-density lipoprotein (LDL) remains unclear. METHODS: Single-nucleotide polymorphism specific clusters associated with LDL cholesterol (LDL-C), VLDL cholesterol (VLDL-C) and Lp(a) were identified. The relationships of...
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