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Article

Oxidized Phospholipids and Risk of Calcific Aortic Valve Disease: The Copenhagen General Population Study.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2017

Kamstrup Pia R, Hung Ming-Yow, Witztum Joseph L, Tsimikas Sotirios, Nordestgaard Børge G

Abstract excerpt

OBJECTIVE: Lipoprotein(a) is causally associated with calcific aortic valve disease (CAVD). Lipoprotein(a) carries proinflammatory and procalcific oxidized phospholipids (OxPL). We tested whether the CAVD risk is mediated by the content of OxPL on lipoprotein(a). APPROACH AND RESULTS: A case-control study was performed within the Copenhagen General Population Study (n=87 980), including 725 CAVD cases (1977-2013)...

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Identifiers

PMID: 28572160
DOI: 10.1161/ATVBAHA.116.308761
PMCID: PMC5551411

Genes

LPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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