Article
Plasma lipids and risk of aortic valve stenosis: a Mendelian randomization study.
European heart journal - 21 Oct 2020
Nazarzadeh Milad, Pinho-Gomes Ana-Catarina, Bidel Zeinab, Dehghan Abbas, Canoy Dexter, Hassaine Abdelaali, Ayala Solares Jose Roberto, Salimi-Khorshidi Gholamreza, Smith George Davey, Otto Catherine M, Rahimi Kazem
Abstract excerpt
AIMS: Aortic valve stenosis is commonly considered a degenerative disorder with no recommended preventive intervention, with only valve replacement surgery or catheter intervention as treatment options. We sought to assess the causal association between exposure to lipid levels and risk of aortic stenosis. METHODS AND RESULTS: Causality of association was assessed using two-sample Mendelian randomization...
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