Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A polymorphism in the BIN1 gene influences its expression and is associated with the risk of Alzheimer's disease: An integrated analysis.

Journal of Alzheimer's disease : JAD - 1 May 2025

Wang Shitao, Luo Guoshuai, Sun Guangxin, Zhang Mengen, Qin Yaqin, Lu Jinghong, Xu Hui, Li Zongyou

Abstract excerpt

BackgroundThe correlation between rs7561528 and the risk of Alzheimer's disease (AD) has been reported with varying results, and the potential mechanism of rs7561528 in influencing AD risk remains unexplored.ObjectiveThis study aims to examine the impact of rs7561528 on AD risk and to investigate its potential mechanism.MethodsThis study initially synthesized previously published data to investigate the...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Aged
Share to Alzheimer Disease
Share to Brain
Share to Nuclear Proteins
Share to Polymorphism, Single Nucleotide
Share to Tumor Suppressor Proteins
Share to White People

Source

Identifiers

PMID: 40138448
DOI: 10.1177/13872877251326273

Genes

BIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A polymorphism in the BIN1 gene influences its expression and is associated with the risk of Alzheimer's disease: An integrated analysis.PMID 40138448Read ↗

Convergent lines of evidence support BIN1 as a risk gene of Alzheimer's disease.Semantic proximity Read ↗

BIN1 gene rs744373 polymorphism contributes to Alzheimer's disease in East Asian population.Semantic proximity Read ↗

Genetic association of BIN1 and GAB2 in Alzheimer's disease: A meta-analysis and systematic review.Semantic proximity Read ↗

The bridging integrator 1 Gene rs7561528 polymorphism contributes to Alzheimer's disease susceptibility in East Asian and Caucasian populations.Semantic proximity Read ↗

Complex genetic interactions affect susceptibility to Alzheimer's disease risk in the BIN1 and MS4A6A lociSemantic proximity Read ↗

Complex genetic interactions affect susceptibility to Alzheimer's disease risk in the BIN1 and MS4A6A loci.Semantic proximity Read ↗

Common variants at Bin1 are associated with sporadic Alzheimer's disease in the Han Chinese population.Semantic proximity Read ↗

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.Semantic proximity Read ↗

New Insights on Bridging Integrator 1 Protein Isoforms as a Risk Increasing Gene in Alzheimer’s DiseaseSemantic proximity Read ↗

Epistatic genetic effects among Alzheimer's candidate genes.Semantic proximity Read ↗

Bridging Integrator 1 (BIN1) Genotypes Mediate Alzheimer's Disease Risk by Altering Neuronal Degeneration.Semantic proximity Read ↗

Genetic variation in BIN1 gene and Alzheimer's disease risk in Han Chinese individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.