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Article

Genetic variation in BIN1 gene and Alzheimer's disease risk in Han Chinese individuals.

Neurobiology of aging - 1 Jul 2014

Tan Meng-Shan, Yu Jin-Tai, Jiang Teng, Zhu Xi-Chen, Guan Hua-Shi, Tan Lan

Abstract excerpt

Genome-wide association studies have identified the bridging integrator 1 (BIN1) gene as the most important genetic susceptibility locus in late-onset Alzheimer's disease (LOAD) after apolipoprotein E for individuals of European ancestry. To further characterize this association and to isolate the variants within BIN1 contributing to LOAD in Han Chinese individuals, we conducted a 2-step design study in our...

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Source

Identifiers

PMID: 24582639
DOI: 10.1016/j.neurobiolaging.2014.01.151

Genes

BIN1

Variants

rs67327804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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