Article
BIN1 gene rs744373 polymorphism contributes to Alzheimer's disease in East Asian population.
Neuroscience letters - 7 Jun 2013
Liu Guiyou, Zhang Shuyan, Cai Zhiyou, Li You, Cui Lili, Ma Guoda, Jiang Yongshuai, Zhang Liangcai, Feng Rennan, Liao Mingzhi, Chen Zugen, Zhao Bin, Li Keshen
Abstract excerpt
Large-scale genome-wide association studies (GWAS) identified BIN1 gene rs744373 polymorphism to be significantly associated with Alzheimer's disease (AD) in Caucasian ancestry. Recently, this polymorphism was also investigated in East Asian population. However, no study reported significant association. We consider that the failure to replicate significant association between rs744373 polymorphism and AD may be...
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