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Article

Epistatic genetic effects among Alzheimer's candidate genes.

PloS one - 1 Jan 2013

Hohman Timothy J, Koran Mary Ellen, Thornton-Wells Tricia

Abstract excerpt

BACKGROUND: Novel risk variants for late-onset Alzheimer's disease (AD) have been identified and replicated in genome-wide association studies. Recent work has begun to address the relationship between these risk variants and biomarkers of AD, though results have been mixed. The aim of the current study was to characterize single marker and epistatic genetic effects between the top candidate Single Nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24260488
DOI: 10.1371/journal.pone.0080839
PMCID: PMC3832488

Genes

BIN1
PICALM

Provenance

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