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Article

Convergent lines of evidence support BIN1 as a risk gene of Alzheimer's disease.

Human genomics - 30 Jan 2021

Zhu Jin, Liu Xia, Yin Hongtao, Gao Yan, Yu Hao

Abstract excerpt

Genome-wide association studies (GWAS) have identified several susceptibility loci of Alzheimer's disease (AD), which were mainly located in noncoding regions of the genome. Meanwhile, the putative biological mechanisms underlying AD susceptibility loci were still unclear. At present, identifying the functional variants of AD pathogenesis remains a major challenge. Herein, we first used summary data-based...

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Identifiers

PMID: 33516273
DOI: 10.1186/s40246-021-00307-6
PMCID: PMC7847034

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Convergent lines of evidence support BIN1 as a risk gene of Alzheimer's disease.PMID 33516273Read ↗

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