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A Multi-Omics Analysis of an Exhausted T Cells’ Molecular Signature in Pan-Cancer

18 Jul 2024

Abstract excerpt

T cells are essential tumor suppressors in cancer immunology, but their dysfunction induced by cancer cells can result in T cell exhaustion. Exhausted T cells (Tex) significantly influence the tumor immune environment, and thus, there is a need for their thorough investigation across different types of cancer. Here, we address the role of Tex cells in pan-cancer, focusing on the expression, mutations,...

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PMID: 39064019
DOI: 10.3390/jpm14070765

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