Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulatory T-cell Genes Drive Altered Immune Microenvironment in Adult Solid Cancers and Allow for Immune Contextual Patient Subtyping

13 Nov 2017

Abstract excerpt

Abstract Background: The tumor microenvironment is an important factor in cancer immunotherapy response. To further understand how a tumor affects the local immune system, we analyzed immune gene expression differences between matching normal and tumor tissue. Methods: We analyzed public and new gene expression data from solid cancers and isolated immune cell populations. We also determined the correlation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29133367
DOI: 10.1158/1055-9965.epi-17-0461

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulatory T-cell Genes Drive Altered Immune Microenvironment in Adult Solid Cancers and Allow for Immune Contextual Patient SubtypingPMID 29133367Read ↗

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory CellsSemantic proximity Read ↗

Revealing the role of regulatory T cells in the tumor microenvironment of lung adenocarcinoma: a novel prognostic and immunotherapeutic signatureSemantic proximity Read ↗

Identification of an immune gene expression signature associated with favorable clinical features in Treg-enriched patient tumor samplesSemantic proximity Read ↗

Identification of an immune gene expression signature associated with favorable clinical features in Treg-enriched patient tumor samplesSemantic proximity Read ↗

An atlas of genetic effects on cellular composition of the tumor microenvironment.Semantic proximity Read ↗

Integrative analysis of the immunological features and immunotherapy response of positive regulators of T cell function in colorectal cancerSemantic proximity Read ↗

Site-dependent Treg cell transcriptional reprograming in a metastatic colorectal cancer model holds prognostic significanceSemantic proximity Read ↗

Comprehensive evaluation of immunological attributes and immunotherapy responses of positive T cell function regulators in colorectal cancer.Semantic proximity Read ↗

Single‐cell analyses reveal suppressive tumor microenvironment of human colorectal cancerSemantic proximity Read ↗

Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy responseSemantic proximity Read ↗

Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma.Semantic proximity Read ↗

Pan-cancer characterization of lncRNA modifiers of immune microenvironment reveals clinically distinct de novo tumor subtypesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.