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Pan-cancer analysis of ITGB3 as a potential prognostic and immunological biomarker

12 Apr 2025

Abstract excerpt

Integrin β3 (ITGB3) acts as a crucial regulator and target within the tumor immune microenvironment (TIME) and is highly expressed in the TIME of various tumors. The TIMER, TCGA, GTEx, and CCLE databases were utilized to comprehensively analyze the differential expression of ITGB3 in tumor tissues. Kaplan-Meier analysis, forest plots, and univariate and multivariate Cox regression were used to assess the genetic...

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PMID: 40220261
DOI: 10.1007/s12672-025-02300-0

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