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Appraising histone H4 lysine 5 lactylation as a novel biomarker in breast cancer

10 Mar 2025

Abstract excerpt

Background Posttranslational modifications of histone lysine (K) have integral connections with cell metabolism, and participate in the carcinogenesis of various cancers. This study focuses on evaluating the expression of histone H4 lys 5 lactylation (H4K5lac) and its clinical role in breast cancer (BC). Methods During this research, immunohistochemistry (IHC) and immunoblotting, utilizing a specific primary...

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Share to Epigenetics and DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40065036
DOI: 10.1038/s41598-025-92666-6

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