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Lactylated histone H3K18 as a potential biomarker for the diagnosis and prediction of the severity of pancreatic cancer

25 Nov 2024

Abstract excerpt

BACKGROUND: Lactylation plays an essential role in pancreatic cancer, but the precise role of lactylated histone in the diagnosis and prognosis of pancreatic cancer remains to be further clarified. METHODS: Twenty-one patients diagnosed with pancreatic cancer were enrolled in this study, and the clinicopathologic characteristics were collected. Lactylation levels of total proteins and histone H3 Lysine-18 (H3K18)...

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PMID: 39591911
DOI: 10.1016/j.clinsp.2024.100544

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