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Article

Lysine lactylation (Kla) might be a novel therapeutic target for breast cancer

10 Nov 2023

Abstract excerpt

BACKGROUND: Histone lysine lactylation (Kla) is a newly identified histone modification, which plays a crucial role in cancer progression. Hence, we determined the prognostic value of Kla in breast cancer (BC). METHODS: We obtained RNA expression profiles of BC from The Cancer Genome Atlas (TCGA), following screening out Kla-specific genes. Furthermore, we determined the prognostic value of Kla by constructing a...

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PMID: 37950222
DOI: 10.1186/s12920-023-01726-1

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