Article
Genetic risk for schizophrenia and brain activation during the Penn Conditional Exclusion Test: A multiplex extended pedigree study.
Journal of psychopathology and clinical science - 1 Apr 2025
Rupert Petra E, Roalf David R, Prasad Konasale M, Kuo Susan S, Musket Christie W, Wood Joel, Gur Ruben C, Almasy Laura, Gur Raquel E, Nimgaonkar Vishwajit L, Pogue-Geile Michael F
Abstract excerpt
Individuals with schizophrenia have poorer performance and often differing patterns of brain activation compared to controls on a variety of cognitive tasks, including those that require inhibition of responses and shifting to new responses. This study sought to examine the degree to which performance on a task developed to measure cognitive flexibility, the Penn Conditional Exclusion Test (PCET), and its related...
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