Article
Effects of a genome-wide supported psychosis risk variant on neural activation during a theory-of-mind task.
Molecular psychiatry - 1 Apr 2011
Walter H, Schnell K, Erk S, Arnold C, Kirsch P, Esslinger C, Mier D, Schmitgen M M, Rietschel M, Witt S H, Nöthen M M, Cichon S, Meyer-Lindenberg A
Abstract excerpt
Schizophrenia is associated with marked deficits in theory of mind (ToM), a higher-order form of social cognition representing the thoughts, emotions and intentions of others. Altered brain activation in the medial prefrontal cortex and temporo-parietal cortex during ToM tasks has been found in patients with schizophrenia, but the relevance of these neuroimaging findings for the heritable risk for schizophrenia...
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