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Article

Genetic complementation between UV-sensitive CHO mutants and xeroderma pigmentosum fibroblasts.

Mutation research - 1 Jan 2000

Thompson L H, Mooney C L, Brookman K W

Abstract excerpt

The purpose of this study was to determine the feasibility of doing complementation analysis between DNA-repair mutants of CHO cells and human fibroblasts based on the recovery of hybrid cells resistant to DNA damage. Two UV-sensitive CHO mutant lines, UV20 and UV41, which belong to different genetic complementation groups, were fused with fibroblasts of xeroderma pigmentosum in various complementation groups....

Topics

Animals
Cell Survival
Cricetinae
Cricetulus
DNA Repair
Female
Genetic Complementation Test
Humans
Hybrid Cells
Mutation
Ovary
Ultraviolet Rays

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Xeroderma Pigmentosum

Source

Identifiers

PMID: 4000167
DOI: 10.1016/0027-5107(85)90139-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-4000167-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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