Article
The effect of thymidine on the induction of micronuclei by alkylating agents in V79 Chinese hamster cells.
Mutation research - 1 Jan 2000
Bonatti S, Simi L, Abbondandolo A
Abstract excerpt
Incubation in thymidine-containing medium resulted in increased lethality and micronucleus frequency in V79 cells treated with ethyl nitrosourea (ENU), methyl nitrosourea (MNU) and ethyl methane-sulphonate (EMS) but not with methyl methanesulfonate (MMS). Thymidine had no effect in ENU treated HeLa cells. In V79 cells, the presence of thymidine during post-treatment DNA replication was necessary for the effect....
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