Induction of micronuclei, DNA strand breaks and HPRT mutations in cultured Chinese hamster V79 cells by the phytoestrogen coumoestrol.

doi:10.1016/s0278-6915(97)00022-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Induction of micronuclei, DNA strand breaks and HPRT mutations in cultured Chinese hamster V79 cells by the phytoestrogen coumoestrol.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Jun 1997

Kulling S E, Metzler M

Abstract excerpt

Coumoestrol (COUM), genistein (GEN) and daidzein (DAI) are major phytoestrogens present in numerous plants eaten by humans and food-producing animals. Little is known about the genotoxicity of these natural compounds. The effects of COUM, GEN and DAI were studied in cultured Chinese hamster V79 c...

Topics

Animals
Cell Survival
Cells, Cultured
Coumestrol
Cricetinae
Cricetulus
DNA Damage
Estrogens, Non-Steroidal
Fibroblasts
Genistein
Hypoxanthine Phosphoribosyltransferase
Isoflavones
Lung
Micronuclei, Chromosome-Defective
Mutagenicity Tests
Mutation

Source

Open in PubMed

Identifiers

PMID: 9225019
DOI: 10.1016/s0278-6915(97)00022-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9225019-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics