Article
The influence of multiple mutagenic treatments on the occurrence of 6-thioguanine-resistant mutants in dividing V79 cells.
Mutation research - 1 Jan 2000
Slamenová D, Gabelová A
Abstract excerpt
Repeated treatments of dividing Chinese hamster V79 cells with ultraviolet radiation or a simple monofunctional alkylating agent (methyl methanesulphonate, N-methyl-N'-nitro-N-nitrosoguanidine or N-methyl-N-nitrosourea) were studied with regard to the pattern of cumulative increase of 6-thioguanine-resistant mutants in the surviving population. There were 5-10 divisions of surviving cells between two successive...
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