Article
Differences between survival, mutagenicity and DNA replication in MMS- and MNU-treated V79 hamster cells.
Mutation research - 1 Jan 1990
Slamenová D, Dusinská M, Bastlová T, Gábelová A
Abstract excerpt
After treatment with methyl methanesulfonate (MMS) or N-methyl-N-nitrosourea (MNU), the mutagenicity and survival of Chinese hamster V79 cells were investigated, as well as the inhibition of daughter DNA synthesis and, using the DNA unwinding technique and hydroxylapatite chromatography, the char...
Topics
- Animals
- Cell Line
- Cell Survival
- Chromatography, Liquid
- Cricetinae
- Cricetulus
- DNA
- DNA Repair
- DNA Replication
- DNA, Single-Stranded
- Methyl Methanesulfonate
- Methylnitrosourea
- Mutagenicity Tests
- Mutation
