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Differences between survival, mutagenicity and DNA replication in MMS- and MNU-treated V79 hamster cells.

Mutation research - 1 Jan 1990

Slamenová D, Dusinská M, Bastlová T, Gábelová A

Abstract excerpt

After treatment with methyl methanesulfonate (MMS) or N-methyl-N-nitrosourea (MNU), the mutagenicity and survival of Chinese hamster V79 cells were investigated, as well as the inhibition of daughter DNA synthesis and, using the DNA unwinding technique and hydroxylapatite chromatography, the character of the newly synthesized DNA was studied. It was found that different cytotoxicity and mutagenicity of MMS and...

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Identifiers

PMID: 2300062
DOI: 10.1016/0027-5107(90)90017-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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