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Interplay of Polygenic Risk Score, Smoking Statuses, and Air Pollution on Lung Adenocarcinoma Risk in a Taiwanese Population.

Respirology (Carlton, Vic.) - 1 Apr 2025

Chen I-Chieh, Chen Yi-Ming, Yang Hui-Wen, Tseng Jeng-Sen, Yang Tsung-Ying

Abstract excerpt

BACKGROUND AND OBJECTIVE: We determined the impact of genetic susceptibility and its interaction with smoking and air pollution on the risk of developing lung adenocarcinoma. METHODS: This retrospective case-control study utilised data from Taiwan Precision Medicine Initiative (TPMI) project conducted between June 2019 and November 2022. The study population consisted of lung adenocarcinoma patients and 1:4 age-,...

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PMID: 39956994
DOI: 10.1111/resp.70004

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