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Article

Clinico-Genomic Interrogation of Secondary-Type Acute Myeloid Leukemia: Response and Outcomes to Contemporary Therapies.

American journal of hematology - 1 May 2025

Senapati Jayastu, Loghavi Sanam, Marvin-Peek Jennifer, Garcia-Manero Guillermo, Kadia Tapan M, Borthakur Gautam, Daver Naval, Short Nicholas J, Jain Nitin, Issa Ghayas C, Haddad Fadi, Hammond Danielle, Chien Kelly, Tang Guillin, Thakral Beenu, Montalban-Bravo Guillermo, Pemmaraju Naveen, Bazinet Alexandre, Swaminathan Mahesh, Pierce Sherry, Abbas Hussein A, Reville Patrick, Popat Uday, Shpall Elizabeth, Champlin Richard, Jabbour Elias, Ravandi Farhad, Kantarjian Hagop M, DiNardo Courtney D

Abstract excerpt

Ontogeny of acute myeloid leukemia (AML) provides prognostic information, however closer interrogation with respect to AML characteristics, genomics, and various treatments are warranted. We defined untreated clinical secondary (CS) AML as AML with a diagnosis of antecedent myelodysplastic syndrome (MDS) or MDS/myeloproliferative neoplasm (MDS-MPN) without exposure to hypomethylating agents or chemotherapy;...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39921561
DOI: 10.1002/ajh.27628
PMCID: PMC13334839

Genes

CS
ELN
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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