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Article

Genetic and Genomic Landscape of Secondary and Therapy-Related Acute Myeloid Leukemia.

Genes - 6 Jul 2020

Higgins Alexandra, Shah Mithun Vinod

Abstract excerpt

A subset of acute myeloid leukemia (AML) arises either from an antecedent myeloid malignancy (secondary AML, sAML) or as a complication of DNA-damaging therapy for other cancers (therapy-related myeloid neoplasm, t-MN). These secondary leukemias have unique biological and clinical features that distinguish them from de novo AML. Over the last decade, molecular techniques have unraveled the complex subclonal...

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Identifiers

PMID: 32640569
DOI: 10.3390/genes11070749
PMCID: PMC7397259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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