Article
Comparative Analysis of ICC and WHO Classifications Reveals Molecular and Clinical Convergence Between AML-MR and MDS/AML.
Hematological oncology - 1 Mar 2026
Wei Yanhui, Yan Xin, Ma Jiale, Cai Zhimei, Guo Xuejun, Miao Zhaoxu, Zhang Zhenjiang, Dai Yingchun, Gao Xiaohui, Ge Zheng
Abstract excerpt
The 2022 WHO and ICC classifications introduced conflicting definitions for myelodysplasia-related acute myeloid leukemia (AML-MR) and myelodysplastic syndrome/AML (MDS/AML), leading to diagnostic uncertainty. This study compared the molecular and clinical characteristics of these entities to clarify their relationship. We conducted a multicenter retrospective study of 568 AML and 75 MDS/AML patients from a...
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