Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia.

doi:10.1182/bloodadvances.2023009675

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia.

Blood advances - 12 Sept 2023

McCarter Joseph G W, Nemirovsky David, Famulare Christopher A, Farnoud Noushin, Mohanty Abhinita S, Stone-Molloy Zoe S, Chervin Jordan, Ball Brian J, Epstein-Peterson Zachary D, Arcila Maria E, Stonestrom Aaron J, Dunbar Andrew, Cai Sheng F, Glass Jacob L, Geyer Mark B, Rampal Raajit K, Berman Ellin, Abdel-Wahab Omar I, Stein Eytan M, Tallman Martin S, Levine Ross L, Goldberg Aaron D, Papaemmanuil Elli, Zhang Yanming, Roshal Mikhail, Derkach Andriy, Xiao Wenbin

Abstract excerpt

Accurate classification and risk stratification are critical for clinical decision making in patients with acute myeloid leukemia (AML). In the newly proposed World Health Organization and International Consensus classifications of hematolymphoid neoplasms, the presence of myelodysplasia-related (MR) gene mutations is included as 1 of the diagnostic criteria for AML, AML-MR, based largely on the assumption that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cancer Genomics and Diagnostics

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Myelodysplastic Syndromes

Share to Myeloproliferative Neoplasms: Diagnosis and Treatment

Share to Prognosis

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 37142255
DOI: 10.1182/bloodadvances.2023009675
PMCID: PMC10471939

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia.PMID 37142255Read ↗

Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia: an appraisal of the new WHO and IC classifications and ELN risk stratificationSemantic proximity Read ↗

Comparative Analysis of ICC and WHO Classifications Reveals Molecular and Clinical Convergence Between AML-MR and MDS/AML.Semantic proximity Read ↗

Clinico-Genomic Interrogation of Secondary-Type Acute Myeloid Leukemia: Response and Outcomes to Contemporary Therapies.Semantic proximity Read ↗

Prognostic Score for Myelodysplastic Syndromes Based on Molecular Evolution.Semantic proximity Read ↗

Defining Acute Myeloid Leukemia Ontogeny in Older Patients.Semantic proximity Read ↗

Acute myeloid leukemia ontogeny is defined by distinct somatic mutations.Semantic proximity Read ↗

AML, NOS and AML-MRC as defined by multilineage dysplasia share a common mutation pattern which is distinct from AML-MRC as defined by MDS-related cytogeneticsSemantic proximity Read ↗

Association of Somatic Gene Mutations with Risk of Transformation into Acute Myeloid Leukemia in Patients with Myelodysplastic Syndrome: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

AML classification in the year 2023: How to avoid a Babylonian confusion of languages.Semantic proximity Read ↗

Impact of myelodysplasia‐related and additional gene mutations in intensively treated patients with NPM1‐mutated AMLSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.