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Article

Causal associations between osteoporosis and HBV infection across Asian and European populations: evidence from Mendelian randomization and colocalization analysis.

Frontiers in endocrinology - 1 Jan 2024

Li Zhengnan, Cao Jiarui, Li Ke, Wu Yixin, Luo Zhanpeng, Cao Rui, Cheng Zhiheng, Tian Zhendong, Han Yiyang, Lai Yuping, Wang Bangqi, Chen Shen

Abstract excerpt

Introduction: Clinical studies have demonstrated a potential association between chronic hepatitis caused by hepatitis B virus (HBV) infection and osteoporosis. However, the causal relationship between HBV infection and osteoporosis remains to be determined. Methods: We investigated whether HBV infection is causally associated with osteoporosis using Mendelian randomization (MR) in East Asian and European...

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PMID: 39911237
DOI: 10.3389/fendo.2024.1419303
PMCID: PMC11794126

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