Article
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis.
Clinical reviews in allergy & immunology - 1 Apr 2024
Wu Yi, Qian Qiwei, Liu Qiaoyan, Wang Rui, Pu Xiting, Li Yao, Zhang Huayang, You Zhengrui, Miao Qi, Xiao Xiao, Lian Min, Wang Qixia, Nakamura Minoru, Gershwin M Eric, Li Zhiqiang, Ma Xiong, Tang Ruqi
Abstract excerpt
Osteoporosis is a major clinical problem in many autoimmune diseases, including primary biliary cholangitis (PBC), the most common autoimmune liver disease. Osteoporosis is a major cause of fracture and related mortality. However, it remains unclear whether PBC confers a causally risk-increasing effect on osteoporosis. Herein, we aimed to investigate the causal relationship between PBC and osteoporosis and...
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