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Article

A causal relationship between bone mineral density and breast cancer risk: a mendelian randomization study based on east Asian population.

BMC cancer - 14 Sept 2024

Cheng Ziyang, Xu Hui, Wang Xin, Teng Tao, Li Bin, Cao Zhong, Li Zhichao, Zhang Jiayi, Xuan Jin, Zhang Fengyi, Chen Yaxin, Li Yujie, Wang Wenbo

Abstract excerpt

BACKGROUND: Breast cancer (BC) poses significant burdens on women globally. While past research suggests a potential link between bone mineral density (BMD) and BC risk, findings remain inconsistent. Our study aims to elucidate the causal relationship between BMD and BC in East Asians using bidirectional Mendelian randomization (MR). METHODS: Genetic association data for bone mineral density T-scores (BMD-T) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39277718
DOI: 10.1186/s12885-024-12908-0
PMCID: PMC11401392

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