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Article

Causal association of NAFLD with osteoporosis, fracture and falling risk: a bidirectional Mendelian randomization study

9 Aug 2023

Abstract excerpt

Introduction The causal association between non-alcoholic fatty liver disease (NAFLD) and osteoporosis remains controversial in previous epidemiological studies. We employed a bidirectional two-sample Mendelian analysis to explore the causal relationship between NAFLD and osteoporosis. Method The NAFLD instrumental variables (IVs) were obtained from a large Genome-wide association study (GWAS) meta-analysis...

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PMID: 37621646
DOI: 10.3389/fendo.2023.1215790

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