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Article

Heterogeneity analysis provides evidence for a genetically homogeneous subtype of bipolar-disorder.

PloS one - 1 Jan 2025

McGrouther Caroline C, Rangan Aaditya V, Di Florio Arianna, Elman Jeremy A, Schork Nicholas J, Kelsoe John

Abstract excerpt

BACKGROUND: Bipolar Disorder (BD) is a complex disease. It is heterogeneous, both at the phenotypic and genetic level, although the extent and impact of this heterogeneity is not fully understood. One way to assess this heterogeneity is to look for patterns in the subphenotype data. Because of the variability in how phenotypic data was collected by the various BD studies over the years, homogenizing this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39879180
DOI: 10.1371/journal.pone.0314288
PMCID: PMC11778664

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PGC

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