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Toward a Deeper Understanding of the Genetics of Bipolar Disorder

3 Aug 2015

Abstract excerpt

Bipolar disorder is a common, complex psychiatric disorder characterized by mania and depression. The disease aggregates in families, but despite much effort, it has been difficult to delineate the basic genetic model or identify specific genetic risk factors. Not only single gene Mendelian transmission and common variant hypotheses but also multivariate threshold models and oligogenic quasi-Mendelian modes of...

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PMID: 26283973
DOI: 10.3389/fpsyt.2015.00105

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