Article
Familiality and diagnostic patterns of subphenotypes in the National Institutes of Mental Health bipolar sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2008
Saunders Erika H, Scott Laura J, McInnis Melvin G, Burmeister Margit
Abstract excerpt
Bipolar-related subphenotypes that cluster within families may help identify subsets of patients that are more genetically homogeneous. Environmental or assessment factors that segregate by family may influence estimates of familiality. We aimed to determine familiality of subphenotypes of bipolar disorder (BP), accounting for effects of age, sex, diagnosis, and site/wave of ascertainment. We studied 589 sibships...
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