Article
Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder.
Translational psychiatry - 10 Jan 2017
Charney A W, Ruderfer D M, Stahl E A, Moran J L, Chambert K, Belliveau R A, Forty L, Gordon-Smith K, Di Florio A, Lee P H, Bromet E J, Buckley P F, Escamilla M A, Fanous A H, Fochtmann L J, Lehrer D S, Malaspina D, Marder S R, Morley C P, Nicolini H, Perkins D O, Rakofsky J J, Rapaport M H, Medeiros H, Sobell J L, Green E K, Backlund L, Bergen S E, Juréus A, Schalling M, Lichtenstein P, Roussos P, Knowles J A, Jones I, Jones L A, Hultman C M, Perlis R H, Purcell S M, McCarroll S A, Pato C N, Pato M T, Craddock N, Landén M, Smoller J W, Sklar P
Abstract excerpt
We performed a genome-wide association study of 6447 bipolar disorder (BD) cases and 12 639 controls from the International Cohort Collection for Bipolar Disorder (ICCBD). Meta-analysis was performed with prior results from the Psychiatric Genomics Consortium Bipolar Disorder Working Group for a combined sample of 13 902 cases and 19 279 controls. We identified eight genome-wide significant, associated regions,...
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