Article

Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scores

2020-04-04

Abstract excerpt

Bipolar disorder (BD) has high clinical heterogeneity, frequent psychiatric comorbidities, and elevated suicide risk. To determine genetic differences between common clinical sub-phenotypes of BD, we performed a systematic PRS analysis using multiple polygenic risk scores (PRSs) from a range of psychiatric, personality, and lifestyle traits to dissect differences in BD sub-phenotypes in two BD cohorts: the Mayo Cl...

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Literature Corpus work: c9e1cc2a-6cd9-526a-b3cc-acbc6d7f2e7f
DOI: 10.1101/2020.03.31.20044800

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