Back to search

Article

Phenome-wide Mendelian Randomization Analysis of Genetic Variants Linking Intracranial Aneurysm, Unruptured Aneurysm, and Subarachnoid Hemorrhage

2024-12-02

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Emerging observational studies showed that intracranial aneurysm (IA) was associated with a variety of diseases. However, the causal nature of these associations is uncertain. <bold>Method:</bold> Based on the GWAS summary data of IA, unruptured IA (UIA) and nontraumatic subarachnoid hemorrhages (SAH), we strictly selected instrumental variables. Through ph...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ff3f42e6-24a3-5790-9c00-eaa29879d271
DOI
10.21203/rs.3.rs-5374565/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Phenome-wide Mendelian Randomization Analysis of Genetic Variants Linking Intracranial Aneurysm, Unruptured Aneurysm, and Subarachnoid HemorrhageDOI 10.21203/rs.3.rs-5374565/v1
Genetic susceptibility and potential therapeutic targets of unruptured intracranial aneurysms: A genome-wide study based on Mendelian randomization.Semantic proximity
A two-sample Mendelian randomization analysis of modifiable risk factors and intracranial aneurysms.Semantic proximity
Sex differences in risk factor relationships with subarachnoid haemorrhage and intracranial aneurysms: A Mendelian Randomisation study.Semantic proximity
Atherosclerosis, Intracranial Aneurysms, and Intermediate Biomarkers: Real-World Observational and Mendelian Randomization ResearchSemantic proximity
Genome-Wide Association Study and Fine Mapping Uncover Key Genetic Loci and Credible Genes of Intracranial Aneurysm and Aneurysmal Subarachnoid Hemorrhage.Semantic proximity
Causal relationship between intracranial aneurysms and COVID-19: A bidirectional two-sample Mendelian randomization studySemantic proximity
Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors.Semantic proximity
Risk Factors for Intracerebral Hemorrhage: Genome-Wide Association Study and Mendelian Randomization Analyses.Semantic proximity
Genetically Determined Smoking Behavior and Risk of Nontraumatic Subarachnoid Hemorrhage.Semantic proximity
Modifiable lifestyle factors and risk of intracranial aneurysm: A univariate and multivariate Mendelian randomisation study.Semantic proximity
Impact of blood pressure and antihypertensive drug classes on intracranial aneurysm: a Mendelian randomization study.Semantic proximity
Genetic risk score for intracranial aneurysms to predict aneurysmal subarachnoid hemorrhage and identify associations with patient characteristicsSemantic proximity
Select a neighboring publication to make it the new centre.