Article
Neutral drift upon threshold-like selection promotes variation in antibiotic resistance phenotype.
Nature communications - 30 Dec 2024
Erdoğan Ayşe Nisan, Dasmeh Pouria, Socha Raymond D, Chen John Z, Life Benjamin E, Jun Rachel, Kiritchkov Linda, Kehila Dan, Serohijos Adrian W R, Tokuriki Nobuhiko
Abstract excerpt
Heritable phenotypic variation plays a central role in evolution by conferring rapid adaptive capacity to populations. Mechanisms that can explain genetic diversity by describing connections between genotype and organismal fitness have been described. However, the difficulty of acquiring comprehensive data on genotype-phenotype-environment relationships has hindered the efforts to explain how the ubiquitously...
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