Article
Allele and genotype frequencies of CYP2B6 and CYP2C19 polymorphisms in Egyptian agricultural workers.
Journal of toxicology and environmental health. Part A - 1 Jan 2012
Ellison Corie A, Abou El-Ella Soheir S, Tawfik Maha, Lein Pamela J, Olson James R
Abstract excerpt
Genetic variability in cytochrome P-450 (CYP) has the potential to modify pharmacological and toxicological responses to many chemicals. Both CYP2B6 and CYP2C19 are pharmacologically and toxicologically relevant due to their ability to metabolize multiple drugs and environmental contaminants, including the organophosphorus (OP) pesticide chlorpyrifos. The aim of this study was to determine the prevalence of...
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