Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-23R is a senescence-linked circulating and tissue biomarker of aging

10 Dec 2024

Abstract excerpt

Cellular senescence is an aging mechanism characterized by cell cycle arrest and a senescence-associated secretory phenotype (SASP). Preclinical studies demonstrate that senolytic drugs, which target survival pathways in senescent cells, can counteract age-associated conditions that span several organs. The comparative efficacy of distinct senolytic drugs for modifying aging and senescence biomarkers in vivo has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Psoriasis: Treatment and Pathogenesis
Share to Skin Protection and Aging
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39658621
DOI: 10.1038/s43587-024-00752-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-23R is a senescence-linked circulating and tissue biomarker of agingPMID 39658621Read ↗

Age- and Tissue-Specific Expression of Senescence Biomarkers in MiceSemantic proximity Read ↗

Targeting Cellular Senescence for Age-Related Diseases: Path to Clinical TranslationSemantic proximity Read ↗

A proteomic atlas of senescence-associated secretomes for aging biomarker development.Semantic proximity Read ↗

A Proteomic Atlas of Senescence-Associated Secretomes for Aging Biomarker DevelopmentSemantic proximity Read ↗

Biomarkers of cellular senescence and major health outcomes in older adultsSemantic proximity Read ↗

Senolytic treatment with fisetin reverses age-related endothelial dysfunction partially mediated by SASP factor CXCL12Semantic proximity Read ↗

Biomarkers of cellular senescence and risk of death in humans.Semantic proximity Read ↗

Senolytics: A Translational Bridge Between Cellular Senescence and Organismal AgingSemantic proximity Read ↗

Measuring the Senescence-Associated Secretory PhenotypeSemantic proximity Read ↗

Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice.Semantic proximity Read ↗

Plasma proteomics identify novel biomarkers and dynamic patterns of biological agingSemantic proximity Read ↗

Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.