Article
Genomic differences of patients with hematologic malignancies in different age groups.
Communications biology - 6 Dec 2024
Yang Xiaodi, Wang Qian, Sun Yuhua, Zhang Ziding, Wuchty Stefan, Liang Zeyin, Dong Yujun
Abstract excerpt
Hematologic malignancies cause significant morbidity/mortality in both children and young adults (CYAs) as well as older adults (OAs). Yet their biological underpinnings remain inadequately understood. Here, we analyzed clinical and genomic disparities between CYAs and OAs in various hematologic malignancies. We found substantial differences in clinical features such as patient sex, ethnicity, metastasis rates,...
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