Article
Genomic disparities between cancers in adolescent and young adults and in older adults.
Nature communications - 24 Nov 2022
Wang Xiaojing, Langevin Anne-Marie, Houghton Peter J, Zheng Siyuan
Abstract excerpt
Cancers cause significant mortality and morbidity in adolescents and young adults (AYAs), but their biological underpinnings are incompletely understood. Here, we analyze clinical and genomic disparities between AYAs and older adults (OAs) in more than 100,000 cancer patients. We find significant differences in clinical presentation between AYAs and OAs, including sex, metastasis rates, race and ethnicity, and...
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